Dr Elise Laperrousaz is a Research Associate in the Fawcett-Martin group, at the John Van Geest Centre for Brain Repair, University of Cambridge. She is working on axonal regeneration in the context of a Central Nervous System injury. She is currently developing an animal model of spinal cord injury to improve axonal regeneration by restoring the transport of integrins through the axon.
Prior to her position in Cambridge, she worked for a pharmaceutical company in France.
Elise completed her PhD at Paris Diderot University, working on the role of an enzymatic disruption of brain lipid metabolism in the onset of metabolic diseases (diabetes, obesity).
Outside of the lab, she likes playing and listening to music – with a great passion for Bach -, tasting French wine and Scottish whisky, hiking and she recently started to row on the Cam.
Neuronal regeneration, Neurodegenerative diseases, Central Nervous System Injury
PhD - Neurophysiology (Paris Diderot University)
MSc - Cellular Biology, Physiology, Physiopathology (Paris Diderot University)
BA – Biomedical Sciences: Biology, Chemistry, Physics (Paris Descartes University)
The hydrolysis of lipoproteins in the Central Nervous System: a new actor in the regulation of energy balance.
- Laperrousaz E, Denis RG, Kassis N, Contreras C, López M, Luquet S, Cruciani-Guglielmacci C, Magnan C. (2018), “Lipoprotein Lipase Expression in Hypothalamus Is Involved in the Central Regulation of Thermogenesis and the Response to Cold Exposure” Front. Endocrinol. 9: 103
- Gao Y, Layritz C, Legutko B, Eichmann TO, Laperrousaz E, Moullé VS, Cruciani-Guglielmacci C, Magnan C, Luquet S, Woods SC, Eckel RH, Yi CX, Garcia-Caceres C, Tschöp MH. (2017), “Disruption of Lipid Uptake in Astroglia Exacerbates Diet-Induced Obesity.” Diabetes 66(10):2555-2563
- Laperrousaz E, Moullé VS, Denis RG, Kassis N, Berland C, Colsch B, Fioramonti X, Philippe E, Lacombe A, Vanacker C, Butin N, Bruce KD, Wang H, Wang Y, Gao Y, Garcia-Caceres C, Prévot V, Tschöp MH, Eckel RH, Le Stunff H, Luquet S, Magnan C, Cruciani-Guglielmacci C. (2017), “Lipoprotein lipase in hypothalamus is a key regulator of body weight gain and glucose homeostasis in mice.” Diabetologia 60(7):1314-1324