Dr Ioana Olan
Dr Olan's research focuses on the epigenetic features of cellular senescence. She is a computational biologist in the Narita Lab at Cancer Research UK Cambridge Institute and she develops methods for analysing (epi)genomics data, and in particular, chromatin architecture assays.
Olan, I., Ando-Kuri, M., Parry, A.J. et al. HMGA1 orchestrates chromatin compartmentalization and sequesters genes into 3D networks coordinating senescence heterogeneity. Nat Commun 15, 6891 (2024).
Olan, I., Handa, T., Narita, M. Beyond SAHF: An integrative view of chromatin compartmentalization during senescence. Current Opinion in Cell Biology 83, 102206 (2023).
Olan, I., Narita, M. Senescence: An Identity Crisis Originating from Deep Within the Nucleus. Annual Review of Cell and Developmental Biology Vol. 38:219-239 (2022).
Olan, I., Parry, A.J., Schoenfelder, S. et al. Transcription-dependent cohesin repositioning rewires chromatin loops in cellular senescence. Nat Commun 11, 6049 (2020).
